While You Were at the Bench: Week 50

The Cassini orbiter has taken photos of a large river system on Saturn’s moon, Titan.  The European Space Agency and NASA have deduced the image shows flowing water, making this the first photographic evidence of a river system beyond Earth.

German researchers have discovered that to fold long strands of DNA into specific shapes (cylindrical, brick-like and cog-like) requires a specific constant temperature for each design.   This technique has reduced the folding time from days to minutes thus making the possibility of DNA nanotechnology realistic.

A group of chemists has successfully developed a non-toxic organic Lithium ion battery using purpurin to react electrochemically with lithium ions.  Extracted from the Madder root and commonly used as a dye in fabrics, purpurin showed similar charge/discharge properties of other conventional inorganic cathodes without the environmental concerns.

Developmental biologists generally agree that human limbs evolved from fish fins and now new research using zebrafish supports a genetic mechanism.  Researchers from Spain increased the activity of Hoxd13 at zebrafish fin tips, leading to the formation of rudimentary limb structures instead of fins.

New research based on the adhesive properties of mussels has led to the development of a bioadhesive gel that can adhere itself to the inside surface of blood vessels.  This bioadhesive gel could be injected into people with atherosclerosis to help prevent rupturing of blood vessels and subsequent blood clots leading to a heart attack or stroke.

Researchers at the University of Pennsylvania have reprogrammed individual patients’ T cells with an HIV-derived lentiviral vector encoded to recognize CD19 proteins commonly expressed on tumor cells.  In a recent Phase 1 clinical trial, 9 out of 12 leukemia patients receiving the treatment are in remission.    On the downside, the T-virus has been created, which never works out well for citizens of Raccoon City.

Have a Great Weekend!

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About Kevin Hascup

Kevin obtained his B.S. in Biochemistry from the University of Delaware in 2001.  He worked in Research & Development for Dade Behring, a clinical diagnostics company located in Newark, Delaware.  It was here that he acquired an interest in neurobiology and in the summer of 2003 he began the PhD program at the University of Kentucky.  In 2007, Kevin obtained his PhD in Anatomy and Neurobiology and continued his thesis research  with two  separate postdoctoral research positions at the Karolinska Institute in Stockholm, Sweden and McGill University in Montreal, Quebec.  Kevin is currently Director of Product Development for an up-and-coming biotechnology located in Springfield, Illinois and is co-founder of RateMyPI.com. 
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